{"id":435,"date":"2023-07-17T21:45:13","date_gmt":"2023-07-17T21:45:13","guid":{"rendered":"https:\/\/vigilantbiosciences.com\/?p=435"},"modified":"2023-07-18T18:09:55","modified_gmt":"2023-07-18T18:09:55","slug":"the-limitations-of-standard-oral-cancer-screening-methods","status":"publish","type":"post","link":"https:\/\/vigilantbiosciences.com\/de\/die-grenzen-der-standardmethoden-zur-fruherkennung-von-mundkrebs\/","title":{"rendered":"Die Grenzen der Standardmethoden zur Fr\u00fcherkennung von Mundkrebs"},"content":{"rendered":"<p>[et_pb_section fb_built=\u201c1\u2033 _builder_version=\u201c4.16\u2033 lock=\u201coff\u201c global_colors_info=\u201c{}\u201c][et_pb_row _builder_version=\u201c4.16\u2033 background_size=\u201cinitial\u201c background_position=\u201ctop_left\u201c background_repeat=\u201crepeat\u201c global_colors_info=\u201c{ }\u201c][et_pb_column type=\u201c4_4\u2033 _builder_version=\u201c4.16\u2033 custom_padding=\u201c|||\u201c global_colors_info=\u201c{}\u201c custom_padding__hover=\u201c|||\u201c][et_pb_text _builder_version=\u201c4.21.0\u2033 header_2_font_size=\u201c24px\u201c header_2_line_height=\u201c1.4em\u201c background_size=\u201cinitial\u201c background_position=\u201ctop_left\u201c background_repeat=\u201crepeat\u201c custom_padding =\u201c25px||||false|false\u201c hover_enabled=\u201c0\u2033 global_colors_info=\u201c{}\u201c sticky_enabled=\u201c0\u2033]Unabh\u00e4ngig von der Krebsart ist eine Diagnose im Fr\u00fchstadium f\u00fcr das \u00dcberleben des Patienten von gr\u00f6\u00dfter Bedeutung. F\u00fcr viele beginnt der Weg zur Diagnose mit einem Screening. Die Krebsvorsorgeuntersuchung dient nicht dazu, eine offizielle Diagnose zu stellen; Mit diesen Untersuchungen k\u00f6nnen jedoch zwei wichtige Ziele erreicht werden: die Krankheit einzud\u00e4mmen und die Sterblichkeitsrate zu senken.<sup>1<\/sup> W\u00e4hrend einige Krebsarten von Natur aus besser erkennbar sind als andere, ist Mundkrebs im Fr\u00fchstadium bekannterma\u00dfen schwer zu diagnostizieren. Dies liegt zum Teil daran, dass aktuelle Screening-Methoden nicht in der Lage sind, b\u00f6sartige Erkrankungen konsistent und genau zu identifizieren. <\/p>\n<h2>Bewertung von Standard-Screening-Protokollen<\/h2>\n<p>Die branchen\u00fcbliche Screening-Methode ist die visuelle orale Untersuchung (VOE), die sowohl visuelle als auch taktile Beurteilungen verwendet, um die Mundh\u00f6hle und den Hals auf abnormales Gewebewachstum oder orale potenziell b\u00f6sartige Erkrankungen (OPMDs) zu untersuchen.<sup>1<\/sup> Einige Anbieter entscheiden sich m\u00f6glicherweise daf\u00fcr, diese Untersuchungen durch lichtbasierte Technologie und\/oder Mundsp\u00fclungen zu erg\u00e4nzen, um klarer zwischen gutartigen und b\u00f6sartigen Neubildungen sowie anderen entz\u00fcndlichen Erkrankungen zu unterscheiden. Sofern verf\u00fcgbar, k\u00f6nnen die Untersuchungen auch Folgendes umfassen:<sup>2<\/sup><\/p>\n<ul>\n<li>Toluidinblau-F\u00e4rbung<\/li>\n<li>Autofluoreszenz<\/li>\n<li>Chemilumineszenz<\/li>\n<li>Zytologie<\/li>\n<li>Schmalbandbildgebung<\/li>\n<\/ul>\n<p class=\" translation-block\">Trotz neuerer Technologie m\u00fcssen diese Zusatzmethoden noch leistungsf\u00e4higere Erkennungsf\u00e4higkeiten als die VOE aufweisen. <sup>2<\/sup> Sie k\u00f6nnen das Vorhandensein einer L\u00e4sion erkennen, k\u00f6nnen jedoch nicht genau angeben, um welchen Typ es sich handelt. Abgesehen von der hohen Rate falsch-positiver Ergebnisse sind diese Screening-Zus\u00e4tze oft kostspielig und komplex und k\u00f6nnen zu unerw\u00fcnschten Nebenwirkungen f\u00fchren. <sup>2<\/sup><\/p>\n<h2>Charakterisierung der idealen Screening-Methode<\/h2>\n<p>Selbst mit der neuesten Screening-Technologie bleibt der VOE der Goldstandard bei der Erkennung von Mundkrebs. Das Fehlen einer fr\u00fchzeitigen Symptomerkennung gef\u00e4hrdet jedoch den Screening-Erfolg und die Patientenergebnisse. Um Mundkrebs zuverl\u00e4ssig zu erkennen, bevor er in die Stadien III und IV eintritt, m\u00fcssen Anbieter Zugang zu einer Screening-Technik haben, die:<\/p>\n<ul>\n<li>Kann am Point-of-Care bei Routineuntersuchungen eingesetzt werden<\/li>\n<li>Ist kosteng\u00fcnstig, nichtinvasiv und relativ schnell<\/li>\n<li>Ber\u00fccksichtigt Lebensstilfaktoren zur individuellen Beurteilung<\/li>\n<li>Bestimmt das Mundkrebsrisiko anhand von Biomarkern genau<\/li>\n<\/ul>\n<p>Wo \u00e4ltere Methoden nicht mithalten konnten, erweisen sich neue Innovationen \u2013 einschlie\u00dflich solcher, die die Analyse von Biomarkern im Speichel nutzen \u2013 als bahnbrechende Neuerungen bei der Erkennung von Mundkrebs. Vigilant Biosciences\u00ae\u00ae ist f\u00fchrend bei der Innovation von Mundkrebs mit klinisch erprobten, datengesteuerten Risikobewertungsl\u00f6sungen, die sowohl den Bed\u00fcrfnissen von Patienten als auch Anbietern gerecht werden, um letztendlich die Ergebnisse zu verbessern.<\/p>\n<p><a href=\"https:\/\/vigilantbiosciences.com\/de\/kontakt\/\">Erfahren Sie mehr dar\u00fcber, wie Vigilant Biosciences\u00ae\u00ae die Technologie zur Erkennung von Mundkrebs ver\u00e4ndert.<\/a>[\/et_pb_text][et_pb_text _builder_version=\u201c4.21.0\u201c text_font_size=\u201c14px\u201c header_2_font_size=\u201c24px\u201c header_2_line_height=\u201c1.4em\u201c background_size=\u201cinitial\u201c background_position=\u201ctop_left\u201c background_repeat=\u201crepeat\u201c global_colors_info=\u201c{}\u201c ]<strong>Quellen<\/strong><\/p>\n<p>1. Warnakulasuriya, S. &amp; Kerr, AR (2021). Mundkrebs-Screening: Vergangenheit, Gegenwart und Zukunft. Journal of Dental Research 100(12), 1313-1320.<br \/>\n2. Kim, DH, Kim, SW, &amp; Hwang, SH (2022). Wirksamkeit nicht-invasiver Diagnosemethoden bei der Diagnose und dem Screening von Mundkrebs und Krebsvorstufen. Brasilianisches Journal f\u00fcr Hals-Nasen-Ohrenheilkunde 88(6), 937-947.[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>","protected":false},"excerpt":{"rendered":"<p>Unabh\u00e4ngig von der Krebsart ist eine Diagnose im Fr\u00fchstadium f\u00fcr das \u00dcberleben des Patienten von gr\u00f6\u00dfter Bedeutung. F\u00fcr viele beginnt der Weg zur Diagnose mit einem Screening. Die Krebsvorsorgeuntersuchung dient nicht dazu, eine offizielle Diagnose zu stellen; Mit diesen Untersuchungen k\u00f6nnen jedoch zwei wichtige Ziele erreicht werden: das Stadium der Krankheit herabzusetzen und die Sterblichkeitsrate zu senken.1 W\u00e4hrend einige Krebsarten [\u2026]<\/p>","protected":false},"author":3,"featured_media":441,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-435","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>The Limitations of Standard Oral Cancer Screening Methods - Vigilant Biosciences\u00ae<\/title>\n<meta name=\"description\" content=\"Explore the limitations of current oral cancer screening methods and how Vigilant Biosciences\u00ae is revolutionizing oral cancer detection.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/vigilantbiosciences.com\/de\/die-grenzen-der-standardmethoden-zur-fruherkennung-von-mundkrebs\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The Limitations of Standard Oral Cancer Screening Methods - 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